Paris, Nov 20 (AFP/APP):At churches, on cruise ships and even in the White House, superspreading events that can sicken dozens, even hundreds, of people have illustrated the potential for the coronavirus to infect in dramatic bursts.
Experts say these large clusters are more than just extreme outliers, but rather the pandemic’s likely main engine of transmission.
And understanding where, when and why they happen could help us tame the spread of the virus in the period before a vaccine may be widely available.
Research increasingly suggests that the coronavirus SARS-CoV-2 does not fan out evenly across the population, but spreads at the extremes in an almost “all or nothing” pattern.
Many studies now suggest the majority of people with Covid-19 barely pass it on to anyone else, but when infections happen they can be explosive and supercharge an outbreak.
Then the virus can infect “10, 20, 50, or even more people”, said Benjamin Althouse, research scientist at the University of Washington’s Institute for Disease Modeling.
This corresponds to the “80/20 rule” of epidemiology, where 80 percent of cases come from only 20 percent of those infected, but Althouse said this coronavirus may be even more extreme, with 90 percent of cases coming from potentially just 10 percent of carriers.
This transmission pattern is like “throwing matches on a pile of kindling”, he told AFP.
“You throw one match, it doesn’t ignite. You throw another match, it doesn’t ignite. You throw yet another match, and this time you see flames blaze up,” he said.
“For SARS-CoV-2, this means that while it is difficult to establish in new places, once established, it can spread rapidly and far.”
Superspreading events have grabbed headlines, looming large in the narrative of the unfolding pandemic.
In February, the Diamond Princess and its 4,000 passengers spent weeks in quarantine at port in Japan as the number of infections on board climbed, reaching 700.
The same month a 61-year-old woman, known as “Patient 31”, attended several church services of the Shincheonji Church of Jesus in the South Korean city of Daegu.
The Korea Centers for Disease Control and Prevention has since linked more than 5,000 infections to Shincheonji.
More recently the virus managed to infiltrate the White House despite a host of measures to keep it out.
Political gatherings, business conferences and sports tournaments have all acted as infection incubators, but these high profile events could just be the tip of the iceberg.
A study by US researchers, based on one of the world’s largest contact tracing operations and published in Science in September, found that “superspreading predominated” in transmission.
Analysing data from the first four months of the pandemic in the states of Tamil Nadu and Andhra Pradesh in India, the authors found that just eight percent of infected individuals accounted for 60 percent of new cases, while 71 percent of people with the virus did not pass it on to any of their contacts.
Perhaps this should not be a surprise.
Maria Van Kerkhove, an infectious disease epidemiologist at the heart of the World Health Organization’s pandemic response, tweeted in October that “superspreading is a hallmark” of coronaviruses.
Indeed, it has been observed in many infectious diseases.
One of the most famous superspreaders was Mary Mallon, a cook working in New York in the early 1900s who was the first documented healthy carrier of typhoid bacteria in the US.
Blamed for giving the illness to dozens of people, she was given the unsympathetic label “Typhoid Mary” and forcibly confined for years.
Measles, smallpox and Ebola also see clustering patterns, as did the other coronaviruses, SARS and MERS.
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